Lee J, Manon V, Chen J. Nucleotide-dependent conformational changes direct peptide export by the transporter associated with antigen processing. Immunity. 2025 Aug 23;. doi: 10.1016/j.immuni.2025.08.003. PubMed PMID: 40885191.

Lee J*, Manon V*, Chen J. A Structural Atlas of TAP Inhibition by Herpesviruses and Poxviruses.bioRxiv. 2025 Jun 20;. doi: 10.1101/2025.06.19.660632. PubMed PMID: 40611894; PubMed Central PMCID: PMC12224542.

Lee J, Manon V, Chen J. Nucleotide-dependent conformational changes direct peptide export by the transporter associated with antigen processing. bioRxiv. 2025 Jun 17;. doi: 10.1101/2025.06.12.659373. PubMed PMID: 40666987; PubMed Central PMCID: PMC12262423.

Lee J, Oldham ML, Manon V, Chen J. Principles of peptide selection by the transporter associated with antigen processing. Proc Natl Acad Sci U S A. 2024 Jun 4;121(23):e2320879121. doi: 10.1073/pnas.2320879121. Epub 2024 May 28. PubMed PMID: 38805290; PubMed Central PMCID: PMC11161800.

Zhao H*, Lee J*, Chen J. The hemolysin A secretion system is a multi-engine pump containing three ABC transporters. Cell. 2022 Sep 1;185(18):3329-3340.e13. doi: 10.1016/j.cell.2022.07.017. PubMed PMID: 36055198.

Liu F, Lee J, Chen J. Molecular structures of the eukaryotic retinal importer ABCA4. Elife. 2021 Feb 19;10. doi: 10.7554/eLife.63524. PubMed PMID: 33605212; PubMed Central PMCID: PMC7932691.

Tomasek D, Rawson S, Lee J, Wzorek JS, Harrison SC, Li Z, Kahne D. Structure of a nascent membrane protein as it folds on the BAM complex. Nature. 2020 Jul;583(7816):473-478. doi: 10.1038/s41586-020-2370-1. Epub 2020 Jun 11. PubMed PMID: 32528179; PubMed Central PMCID: PMC7367713.

Lee J, Tomasek D, Santos TM, May MD, Meuskens I, Kahne D. Formation of a β-barrel membrane protein is catalyzed by the interior surface of the assembly machine protein BamA. Elife. 2019 Nov 14;8. doi: 10.7554/eLife.49787. PubMed PMID: 31724945; PubMed Central PMCID: PMC6887485.

Mandler MD, Baidin V, Lee J, Pahil KS, Owens TW, Kahne D. Novobiocin Enhances Polymyxin Activity by Stimulating Lipopolysaccharide Transport. J Am Chem Soc. 2018 Jun 6;140(22):6749-6753. doi: 10.1021/jacs.8b02283. Epub 2018 May 16. PubMed PMID: 29746111; PubMed Central PMCID: PMC5990483.

Lee J, Sutterlin HA*, Wzorek JS*, Mandler MD, Hagan CL, Grabowicz M, Tomasek D, May MD, Hart EM, Silhavy TJ, Kahne D. Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2359-2364. doi: 10.1073/pnas.1711727115. Epub 2018 Feb 20. PubMed PMID: 29463713; PubMed Central PMCID: PMC5877925.

Wzorek JS, Lee J, Tomasek D, Hagan CL, Kahne DE. Membrane integration of an essential β-barrel protein prerequires burial of an extracellular loop. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2598-2603. doi: 10.1073/pnas.1616576114. Epub 2017 Feb 21. PubMed PMID: 28223520; PubMed Central PMCID: PMC5347601.

Lee J*, Xue M*, Wzorek JS, Wu T, Grabowicz M, Gronenberg LS, Sutterlin HA, Davis RM, Ruiz N, Silhavy TJ, Kahne DE. Characterization of a stalled complex on the β-barrel assembly machine.Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8717-22. doi: 10.1073/pnas.1604100113. Epub 2016 Jul 20. PubMed PMID: 27439868; PubMed Central PMCID: PMC4978274.

Phillips AH, Zhang Y, Cunningham CN, Zhou L, Forrest WF, Liu PS, Steffek M, Lee J, Tam C, Helgason E, Murray JM, Kirkpatrick DS, Fairbrother WJ, Corn JE. Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling. Proc Natl Acad Sci U S A.2013 Jul 9;110(28):11379-84. doi: 10.1073/pnas.1302407110. Epub 2013 Jun 25. PubMed PMID: 23801757; PubMed Central PMCID: PMC3710810.

* denotes equal contribution